FERRIC DERISOMALTOSE

Ferric Derisomaltose is an iron-carbohydrate complex containing ferric hydroxide and derisomaltose. It is administered intravenously and is used for iron replacement in patients with iron deficiency and iron deficiency anaemia.

Its applications include intravenous iron replacement for iron deficiency anaemia and iron deficiency associated with conditions such as chronic kidney disease. Approved indications can differ by country and product.

Ferric Derisomaltose contains iron within a carbohydrate matrix. Following intravenous administration, iron is gradually released and becomes available for binding to transferrin and subsequent incorporation into haemoglobin and other iron-containing proteins.

Its stable iron-carbohydrate structure enables controlled release of iron and limits exposure to labile iron, making it suitable for intravenous iron replacement formulations.

Approved formulations of ferric derisomaltose can allow substantial doses of iron to be administered intravenously. Exact dosing depends on the approved formulation and prescribing information.